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EXPRESSION SYSTEMS

SUMOpro Kit

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SUMOpro Fusion Protein Technology.

The use of SUMOpro as a fusion system can dramatically enhance overall protein production through the enhanced protein translation, solubility, and stability. Each SUMO-fusion system requires specific proteases for removal of the fusion partner: for SUMO use SUMO Protease 1, for SUMOstar use SUMOstar Protease, and for SUMOpro-3 use SUMO Protease 2. SUMO proteases are highly specific and robust enzymes that recognize and bind to the tertiary structure of SUMO in order to correctly identify the C-terminal cleavage site on the enzymes active site. With the exception of proline, these proteases will cleave your fusion protein precisely between the C-terminus of SUMO and the N-terminus of the target protein. By recognizing the tertiary structure of the SUMO tag, this system virtually eliminates the ragged ends and non-specific cleavage seen with other proteases.

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LifeSensors presented an overview of ubiquitin proteomics at the 3rd GTC Conference, Ubiquitin Research and Drug Discovery, Las Vegas, February 25-26th, 2013.
Complexity of ubiquitin pathways leads to frequent questions related to identification of ubiquitin pathway enzymes (E3s and DUBs) and their substrates. An overview of biochemical proteomics for drug discovery applications including Ubiquitin Protein Microarray Services from LifeSensors was presented by Christian Loch, Assistant Director, R&D. Visit our website to find additional information about our Ubiquitin Protein Microarrays.
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LifeSensors Inc. appointed 4A Biotech Co.Ltd as another distributor of its innovative reagents and technologies in China
Located at Guanglian Industrial Park, Beijing, 4A Biotech Co.Ltd. is a leading life science product provider in China.
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LifeSensors presents data at FASEB's Ubiquitin & Cellular Regulation meeting June 24th-29th.
Download PDFs of poster #54 "Effect of DUB inhibitor PR-619 on the microtubule network and protein aggregate formation in oligodendroglial cells: Implications for neurodegeneration" and poster #61 "Decoding the information content of ubiquitin chains: Application of linkage-specific TUBES to the ubiquitome" from our Technical Documentation page (bottom of the page).
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