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EXPRESSION SYSTEMS - Insect
Vectors

Baculoviral Expression Vector Systems (BEVS) provide cost-effective alternatives to mammalian systems, while retaining features of higher eukaryotes that lead to greater fidelity of post-translational modification(s) and (if desired) efficient secretion from the cell.

In BEVS, as in most eukaryotes, endogenous SUMO proteases rapidly cleave SUMO fusions in vivo, precluding the use of the traditional SUMO tag for enhancement of expression and facilitation purification of the protein-of-interest (POI). To remedy this problem, LifeSensors developed SUMOstar -- a novel fusion tag which is resistant to cleavage by endogenous SUMO proteases.

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Expression Systems
Insect Vectors     More Information »
pI-Insect (BEVs) Secretory SUMOstar Vector 3106
pI-Insect (BEVS) SUMOstar Intracellular Vector 3101
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LifeSensors presented an overview of ubiquitin proteomics at the 3rd GTC Conference, Ubiquitin Research and Drug Discovery, Las Vegas, February 25-26th, 2013.
Complexity of ubiquitin pathways leads to frequent questions related to identification of ubiquitin pathway enzymes (E3s and DUBs) and their substrates. An overview of biochemical proteomics for drug discovery applications including Ubiquitin Protein Microarray Services from LifeSensors was presented by Christian Loch, Assistant Director, R&D. Visit our website to find additional information about our Ubiquitin Protein Microarrays.
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LifeSensors

LifeSensors Inc. appointed 4A Biotech Co.Ltd as another distributor of its innovative reagents and technologies in China
Located at Guanglian Industrial Park, Beijing, 4A Biotech Co.Ltd. is a leading life science product provider in China.
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LifeSensors

LifeSensors presents data at FASEB's Ubiquitin & Cellular Regulation meeting June 24th-29th.
Download PDFs of poster #54 "Effect of DUB inhibitor PR-619 on the microtubule network and protein aggregate formation in oligodendroglial cells: Implications for neurodegeneration" and poster #61 "Decoding the information content of ubiquitin chains: Application of linkage-specific TUBES to the ubiquitome" from our Technical Documentation page (bottom of the page).
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