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Custom Protein & Peptide Production

LifeSensors
Custom Protein & Peptide Production | Therapeutic Proteins | Licensing our Technology
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LifeSensors

LifeSensors Protein Production Services
You can choose from any of the protein production, purification, and enzymatic activity determination services we offer that best suits your needs. We will provide you with a competitive quote for the purity you requ ire. LifeSensors’ scientists use our proprietary SUMO expression technologies to enhance expression of your protein in prokaryotic, yeast, insect, and mammalian expression systems.

The advantages of SUMO fusion technology are:
  • Enhanced protein expression with our proprietary SUMO systems optimized individually for prokaryotic, yeast, insect, and mammalian hosts
  • Increased solubility of the target protein
  • Efficient tag removal generating high yields of untagged protein of interest with the desired N-terminal amino acid
  • Simple purification methods


Protein Expression, and Purification
  1. Feasibility Studies: Tell us your ideas or supply us with your cDNA and let us do the rest. Our scientific professionals will determine the appropriate expression system to maximize yield or activity for your protein
  2. Molecular Cloning: Your construct will be cloned into one of our SUMO expression vectors.
  3. Protein Expression: We will express your protein in the quantity and the expression system (E. coli, yeast, insect, mammalian) you request.
  4. Protein Purification: We will develop an efficient, cost effective purification scheme for your protein and deliver it in the quantity and purity you specify.
LifeSensors News

HEADLINES

LifeSensors News
 
LifeSensors Launches DiUbiquitin Substrate
A Novel Fluorescent Assay for Ubiquitin Isopeptide Bond Cleavage
MALVERN, PA -- June 29, 2010 --LifeSensors, Inc., a biotechnology company, announces the launch of its novel physiologically relevant diubiquitin substrates for measuring isopeptide bond cleavage (patent applied for). This breakthrough technology, for both basic research and drug discovery targeting the ubiquitin proteasome pathway, offers sensitive, rapid, and robust fluorescent readouts of isopeptidase or de-ubquitylase (DUB) activity.
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LifeSensors

LifeSensors' Gender Sorting Technology Discussed
Feb 9th 2010 | From The Economist online
Dr Butt’s new device is an oestrogen sniffer. It relies on the fact that female embryos produce this hormone in quantity and male ones do not. The sensor uses a fine needle to penetrate both the shell and the allantoic sac of an egg. This sac is a fluid-filled membrane that cushions the embryo and helps it trade carbon dioxide for oxygen from the air. (It is also the membrane that can make peeling a hard-boiled egg such a frustrating affair.)
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LifeSensors

LifeSensors Publishes in Journal of Animal Science
2010 Jan 15.
An estrogen sensor for poultry gender sorting.

Tran HT, Ferrell W, Butt TR.

The need for segregation of poultry based on sex is driven by gender-related differences in growth rate, market age, management practices, and nutritional requirements. Each day, global poultry industry staff would ideally like to determine the gender of >150 million newly hatched birds. Currently, this can be done only manually at the hatchery, which is a virtually impossible undertaking. LifeSensors has developed a facile, rapid, and low cost yeast-based assay that distinguishes male from female embryonated eggs before hatching based on the estrogen level of their allantoic fluid.
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